10 | 20 | 30 | 40 | 50 | 60 | 70 | 80 | 90 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
V | P | E | R | P | E | D | L | E | V | K | E | V | T | K | N | T | V | T | L | T | W | N | P | P | K | Y | D | G | G | S | E | I | I | N | Y | V | L | E | S | R | L | I | G | T | E | K | F | H | K | V | T | N | D | N | L | L | S | R | K | Y | T | V | K | G | L | K | E | G | D | T | Y | E | Y | R | V | S | A | V | N | I | V | G | Q | G | K | P | S | F | C | T | K | P | I | T | C | K | D | E |
V | P | E | R | P | E | D | L | E | V | K | E | V | T | K | N | T | V | T | L | T | W | N | P | P | K | Y | D | G | G | S | E | I | I | N | Y | V | L | E | S | R | L | I | G | T | E | K | F | H | K | V | T | N | D | N | L | L | S | R | K | Y | T | V | K | G | L | K | E | G | D | T | Y | E | Y | R | V | S | A | V | N | I | V | G | Q | G | K | P | S | F | C | T | K | P | I | T | C | K | D | - |
Pin SAV |
Position |
Domain position |
SAV |
Structural Position |
RS |
Q(SASA) |
Disease |
Source |
MAF |
---|---|---|---|---|---|---|---|---|---|
19284 | 1 | V/G | 1 | rs934353226 | 0.5133 | None | gnomAD-3.1.2 | 6.58E-06 | |
19284 | 1 | V/G | 1 | rs934353226 | 0.5133 | None | gnomAD-4.0.0 | 4.38862E-06 | |
19284 | 1 | V/I | 1 | rs377270926 | 0.5133 | None | gnomAD-2.1.1 | 8.52E-06 | |
19284 | 1 | V/I | 1 | rs377270926 | 0.5133 | None | gnomAD-3.1.2 | 1.32E-05 | |
19284 | 1 | V/I | 1 | rs377270926 | 0.5133 | None | gnomAD-4.0.0 | 6.8952E-06 | |
19286 | 3 | E/K | 3 | rs558844442 | 0.4082 | None | gnomAD-3.1.2 | 6.58E-06 | |
19286 | 3 | E/K | 3 | rs558844442 | 0.4082 | None | 1000 genomes | 1.99681E-04 | |
19286 | 3 | E/K | 3 | rs558844442 | 0.4082 | None | gnomAD-4.0.0 | 6.57289E-06 | |
19286 | 3 | E/Q | 3 | rs558844442 | 0.4082 | None | gnomAD-2.1.1 | 4.24E-06 | |
19286 | 3 | E/Q | 3 | rs558844442 | 0.4082 | None | gnomAD-4.0.0 | 2.76979E-06 | |
19287 | 4 | R/C | 4 | rs372710684 | 0.3739 | None | gnomAD-2.1.1 | 3.31E-05 | |
19287 | 4 | R/C | 4 | rs372710684 | 0.3739 | None | gnomAD-3.1.2 | 1.97E-05 | |
19287 | 4 | R/C | 4 | rs372710684 | 0.3739 | None | gnomAD-4.0.0 | 1.18486E-05 | |
19287 | 4 | R/G | 4 | rs372710684 | 0.3739 | None | gnomAD-3.1.2 | 6.58E-06 | |
19287 | 4 | R/G | 4 | rs372710684 | 0.3739 | None | gnomAD-4.0.0 | 6.57748E-06 | |
19287 | 4 | R/H | 4 | rs371422299 | 0.3739 | None | gnomAD-2.1.1 | 6.61E-05 | |
19287 | 4 | R/H | 4 | rs371422299 | 0.3739 | None | gnomAD-3.1.2 | 1.97E-05 | |
19287 | 4 | R/H | 4 | rs371422299 | 0.3739 | None | 1000 genomes | 1.99681E-04 | |
19287 | 4 | R/H | 4 | rs371422299 | 0.3739 | None | gnomAD-4.0.0 | 2.80602E-05 | |
19288 | 5 | P/A | 5 | rs1490097960 | 0.1119 | None | gnomAD-2.1.1 | 4.07E-06 | |
19288 | 5 | P/A | 5 | rs1490097960 | 0.1119 | None | gnomAD-4.0.0 | 1.60208E-06 | |
19288 | 5 | P/R | 5 | None | 0.1119 |
Other |
Literature | None | |
19289 | 6 | E/A | 6 | None | 0.3205 | None | gnomAD-4.0.0 | 1.6007E-06 | |
19289 | 6 | E/K | 6 | rs1031046164 | 0.3205 | None | gnomAD-3.1.2 | 6.58E-06 | |
19289 | 6 | E/K | 6 | rs1031046164 | 0.3205 | None | gnomAD-4.0.0 | 6.57652E-06 | |
19290 | 7 | D/G | 7 | rs749345178 | 0.5583 | None | gnomAD-2.1.1 | 4.06E-06 | |
19290 | 7 | D/G | 7 | rs749345178 | 0.5583 | None | gnomAD-4.0.0 | 1.60019E-06 | |
19290 | 7 | D/H | 7 | rs770980138 | 0.5583 | None | gnomAD-2.1.1 | 8.14E-06 | |
19290 | 7 | D/H | 7 | rs770980138 | 0.5583 | None | gnomAD-4.0.0 | 4.80375E-06 | |
19291 | 8 | L/M | 9 | None | 0.1937 | None | gnomAD-4.0.0 | 6.85515E-07 | |
19291 | 8 | L/Q | 9 | None | 0.1937 | None | gnomAD-4.0.0 | 1.59786E-06 | |
19291 | 8 | L/V | 9 | rs773843429 | 0.1937 | None | gnomAD-2.1.1 | 8.11E-06 | |
19291 | 8 | L/V | 9 | rs773843429 | 0.1937 | None | gnomAD-4.0.0 | 1.37103E-06 | |
19292 | 9 | E/A | 11 | rs1225953212 | 0.4656 | None | gnomAD-2.1.1 | 4.05E-06 | |
19292 | 9 | E/A | 11 | rs1225953212 | 0.4656 | None | gnomAD-4.0.0 | 1.59757E-06 | |
19294 | 11 | K/N | 13 | None | 0.4584 | None | gnomAD-4.0.0 | 1.5964E-06 | |
19296 | 13 | V/I | 15 | rs770490179 | 0.2512 | None | gnomAD-2.1.1 | 8.09E-06 | |
19296 | 13 | V/I | 15 | rs770490179 | 0.2512 | None | gnomAD-4.0.0 | 4.78903E-06 | |
19297 | 14 | T/I | 16 | None | 0.2655 | None | gnomAD-4.0.0 | 1.59534E-06 | |
19297 | 14 | T/S | 16 | None | 0.2655 | None | gnomAD-4.0.0 | 1.59529E-06 | |
19298 | 15 | K/Q | 17 | rs781725039 | 0.5396 | None | gnomAD-2.1.1 | 1.61E-05 | |
19298 | 15 | K/Q | 17 | rs781725039 | 0.5396 | None | gnomAD-4.0.0 | 3.50909E-05 | |
19299 | 16 | N/H | 18 | rs768931487 | 0.4348 | None | gnomAD-2.1.1 | 8.07E-06 | |
19299 | 16 | N/H | 18 | rs768931487 | 0.4348 | None | gnomAD-3.1.2 | 6.57E-06 | |
19299 | 16 | N/H | 18 | rs768931487 | 0.4348 | None | gnomAD-4.0.0 | 5.13313E-06 | |
19300 | 17 | T/A | 19 | rs1303630569 | 0.2101 | None | gnomAD-2.1.1 | 8.07E-06 | |
19300 | 17 | T/A | 19 | rs1303630569 | 0.2101 | None | gnomAD-4.0.0 | 4.78292E-06 | |
19300 | 17 | T/N | 19 | rs979451740 | 0.2101 | None | gnomAD-4.0.0 | 2.73922E-06 | |
19301 | 18 | V/I | 20 | rs1210344440 | 0.1070 | None | gnomAD-3.1.2 | 6.58E-06 | |
19301 | 18 | V/I | 20 | rs1210344440 | 0.1070 | None | gnomAD-4.0.0 | 2.56553E-06 | |
19302 | 19 | T/I | 21 | None | 0.1784 | None | gnomAD-4.0.0 | 1.59357E-06 | |
19302 | 19 | T/P | 21 | rs2051000706 | 0.1784 | None | gnomAD-3.1.2 | 1.31E-05 | |
19302 | 19 | T/P | 21 | rs2051000706 | 0.1784 | None | gnomAD-4.0.0 | 3.8478E-06 | |
19303 | 20 | L/F | 22 | rs868588764 | 0.0965 | None | gnomAD-3.1.2 | 6.58E-06 | |
19303 | 20 | L/M | 22 | rs1395931081 | 0.0965 | None | gnomAD-2.1.1 | 4.03E-06 | |
19303 | 20 | L/M | 22 | rs1395931081 | 0.0965 | None | gnomAD-4.0.0 | 6.84596E-07 | |
19303 | 20 | L/V | 22 | None | 0.0965 | None | gnomAD-4.0.0 | 2.05379E-06 | |
19304 | 21 | T/P | 23 | None | 0.2203 | None | gnomAD-4.0.0 | 3.42283E-06 | |
19305 | 22 | W/S | 24 | None | 0.1100 | None | gnomAD-4.0.0 | 1.36913E-06 | |
19307 | 24 | P/R | 26 | None | 0.3330 | None | gnomAD-4.0.0 | 1.20039E-06 | |
19308 | 25 | P/L | 27 | rs745457069 | 0.1327 | None | gnomAD-2.1.1 | 1.43E-05 | |
19308 | 25 | P/L | 27 | rs745457069 | 0.1327 | None | gnomAD-3.1.2 | 1.32E-05 | |
19308 | 25 | P/L | 27 | rs745457069 | 0.1327 | None | gnomAD-4.0.0 | 1.2822E-05 | |
19309 | 26 | K/M | 28 | None | 0.6691 | None | gnomAD-4.0.0 | 6.8451E-07 | |
19309 | 26 | K/R | 28 | None | 0.6691 | None | gnomAD-4.0.0 | 2.05353E-06 | |
19311 | 28 | D/H | 30 | None | 0.2182 | None | gnomAD-4.0.0 | 1.59247E-06 | |
19312 | 29 | G/D | 31 | rs1559625655 | 0.1858 | None | gnomAD-2.1.1 | 8.05E-06 | |
19312 | 29 | G/D | 31 | rs1559625655 | 0.1858 | None | gnomAD-4.0.0 | 4.79102E-06 | |
19312 | 29 | G/R | 31 | rs753408795 | 0.1858 | None | gnomAD-2.1.1 | 4.03E-06 | |
19312 | 29 | G/R | 31 | rs753408795 | 0.1858 | None | gnomAD-4.0.0 | 1.16354E-05 | |
19312 | 29 | G/S | 31 | rs753408795 | 0.1858 | None | gnomAD-2.1.1 | 7.15E-06 | |
19312 | 29 | G/S | 31 | rs753408795 | 0.1858 | None | gnomAD-3.1.2 | 2.63E-05 | |
19312 | 29 | G/S | 31 | rs753408795 | 0.1858 | None | gnomAD-4.0.0 | 3.71946E-06 | |
19313 | 30 | G/A | 32 | rs777653912 | 0.5244 | None | gnomAD-2.1.1 | 4.03E-06 | |
19313 | 30 | G/A | 32 | rs777653912 | 0.5244 | None | gnomAD-4.0.0 | 1.59243E-06 | |
19313 | 30 | G/R | 32 | None | 0.5244 | None | gnomAD-4.0.0 | 3.1848E-06 | |
19316 | 33 | I/V | 35 | rs756090879 | 0.1334 | None | gnomAD-2.1.1 | 4.02E-06 | |
19316 | 33 | I/V | 35 | rs756090879 | 0.1334 | None | gnomAD-4.0.0 | 1.59234E-06 | |
19317 | 34 | I/L | 36 | rs752651782 | 0.3138 | None | gnomAD-3.1.2 | 6.57E-06 | |
19317 | 34 | I/L | 36 | rs752651782 | 0.3138 | None | gnomAD-4.0.0 | 6.57246E-06 | |
19317 | 34 | I/T | 36 | rs1249290348 | 0.3138 | None | gnomAD-2.1.1 | 4.02E-06 | |
19317 | 34 | I/T | 36 | rs1249290348 | 0.3138 | None | gnomAD-4.0.0 | 3.18466E-06 | |
19317 | 34 | I/V | 36 | rs752651782 | 0.3138 | None | gnomAD-2.1.1 | 4.02E-06 | |
19317 | 34 | I/V | 36 | rs752651782 | 0.3138 | None | gnomAD-4.0.0 | 1.59231E-06 | |
19318 | 35 | N/K | 37 | rs756463146 | 0.1855 | None | gnomAD-2.1.1 | 8.05E-06 | |
19318 | 35 | N/K | 37 | rs756463146 | 0.1855 | None | gnomAD-4.0.0 | 1.64257E-05 | |
19318 | 35 | N/T | 37 | rs767305625 | 0.1855 | None | gnomAD-2.1.1 | 1.61E-05 | |
19318 | 35 | N/T | 37 | rs767305625 | 0.1855 | None | gnomAD-3.1.2 | 1.31E-05 | |
19318 | 35 | N/T | 37 | rs767305625 | 0.1855 | None | gnomAD-4.0.0 | 1.4256E-05 | |
19319 | 36 | Y/C | 38 | rs369082749 | 0.1158 | None | gnomAD-2.1.1 | 2.86E-05 | |
19319 | 36 | Y/C | 38 | rs369082749 | 0.1158 | None | gnomAD-3.1.2 | 3.29E-05 | |
19319 | 36 | Y/C | 38 | rs369082749 | 0.1158 | None | gnomAD-4.0.0 | 2.54148E-05 | |
19321 | 38 | L/P | 40 | rs1395371412 | 0.0974 | None | gnomAD-4.0.0 | 1.5922E-06 | |
19322 | 39 | E/G | 41 | rs2050988778 | 0.1465 | None | gnomAD-4.0.0 | 1.44039E-05 | |
19322 | 39 | E/Q | 41 | None | 0.1465 | None | gnomAD-4.0.0 | 1.59222E-06 | |
19323 | 40 | S/R | 42 | None | 0.1535 | None | gnomAD-4.0.0 | 1.20032E-06 | |
19324 | 41 | R/Q | 43 | rs186809500 | 0.2199 | None | gnomAD-2.1.1 | 7.24E-05 | |
19324 | 41 | R/Q | 43 | rs186809500 | 0.2199 | None | gnomAD-3.1.2 | 5.26E-05 | |
19324 | 41 | R/Q | 43 | rs186809500 | 0.2199 | None | 1000 genomes | 5.99042E-04 | |
19324 | 41 | R/Q | 43 | rs186809500 | 0.2199 | None | gnomAD-4.0.0 | 2.35542E-05 | |
19324 | 41 | R/W | 43 | rs1203435642 | 0.2199 | None | gnomAD-2.1.1 | 8.05E-06 | |
19324 | 41 | R/W | 43 | rs1203435642 | 0.2199 | None | gnomAD-3.1.2 | 6.58E-06 | |
19324 | 41 | R/W | 43 | rs1203435642 | 0.2199 | None | gnomAD-4.0.0 | 6.81886E-06 | |
19326 | 43 | I/F | 50 | None | 0.4724 | None | gnomAD-4.0.0 | 1.20032E-06 | |
19326 | 43 | I/M | 50 | rs763120020 | 0.4724 | None | gnomAD-2.1.1 | 8.04E-06 | |
19326 | 43 | I/M | 50 | rs763120020 | 0.4724 | None | gnomAD-4.0.0 | 3.42184E-06 | |
19326 | 43 | I/T | 50 | rs766571281 | 0.4724 | None | gnomAD-2.1.1 | 1.61E-05 | |
19326 | 43 | I/T | 50 | rs766571281 | 0.4724 | None | gnomAD-4.0.0 | 6.15935E-06 | |
19329 | 46 | E/D | 63 | rs375818281 | 0.9644 | None | gnomAD-2.1.1 | 7.14E-06 | |
19329 | 46 | E/D | 63 | rs375818281 | 0.9644 | None | gnomAD-3.1.2 | 1.32E-05 | |
19329 | 46 | E/D | 63 | rs375818281 | 0.9644 | None | gnomAD-4.0.0 | 1.36875E-06 | |
19329 | 46 | E/Q | 63 | rs975610705 | 0.9644 | None | gnomAD-2.1.1 | 3.19E-05 | |
19329 | 46 | E/Q | 63 | rs975610705 | 0.9644 | None | gnomAD-3.1.2 | 1.32E-05 | |
19329 | 46 | E/Q | 63 | rs975610705 | 0.9644 | None | gnomAD-4.0.0 | 1.31501E-05 | |
19331 | 48 | F/L | 65 | rs1449016899 | 0.1829 | None | gnomAD-2.1.1 | 4.02E-06 | |
19331 | 48 | F/L | 65 | rs1449016899 | 0.1829 | None | gnomAD-4.0.0 | 2.73747E-06 | |
19332 | 49 | H/Q | 66 | rs762362185 | 0.5730 | None | gnomAD-3.1.2 | 6.58E-06 | |
19332 | 49 | H/Q | 66 | rs762362185 | 0.5730 | None | gnomAD-4.0.0 | 6.57661E-06 | |
19332 | 49 | H/Y | 66 | rs770403940 | 0.5730 | None | gnomAD-2.1.1 | 4.02E-06 | |
19332 | 49 | H/Y | 66 | rs770403940 | 0.5730 | None | gnomAD-4.0.0 | 1.59214E-06 | |
19333 | 50 | K/N | 67 | rs777279726 | 0.3191 | None | gnomAD-4.0.0 | 1.59211E-06 | |
19333 | 50 | K/R | 67 | rs1469122729 | 0.3191 | None | gnomAD-2.1.1 | 4.02E-06 | |
19333 | 50 | K/R | 67 | rs1469122729 | 0.3191 | None | gnomAD-4.0.0 | 3.18422E-06 | |
19334 | 51 | V/D | 68 | rs546716167 | 0.2517 | None | gnomAD-2.1.1 | 1.21E-05 | |
19334 | 51 | V/D | 68 | rs546716167 | 0.2517 | None | gnomAD-3.1.2 | 1.32E-05 | |
19334 | 51 | V/D | 68 | rs546716167 | 0.2517 | None | 1000 genomes | 1.99681E-04 | |
19334 | 51 | V/D | 68 | rs546716167 | 0.2517 | None | gnomAD-4.0.0 | 8.67741E-06 | |
19334 | 51 | V/I | 68 | None | 0.2517 | None | gnomAD-2.1.1 | 8.04E-06 | |
19334 | 51 | V/I | 68 | None | 0.2517 | None | gnomAD-3.1.2 | 6.58E-06 | |
19334 | 51 | V/I | 68 | None | 0.2517 | None | gnomAD-4.0.0 | 2.47943E-06 | |
19334 | 51 | V/L | 68 | rs769006307 | 0.2517 | None | gnomAD-3.1.2 | 1.32E-05 | |
19334 | 51 | V/L | 68 | rs769006307 | 0.2517 | None | gnomAD-4.0.0 | 3.09928E-06 | |
19335 | 52 | T/A | 69 | rs752763361 | 0.1806 | None | gnomAD-4.0.0 | 1.20032E-06 | |
19335 | 52 | T/I | 69 | rs878924097 | 0.1806 | None | gnomAD-2.1.1 | 4.02E-06 | |
19335 | 52 | T/I | 69 | rs878924097 | 0.1806 | None | gnomAD-4.0.0 | 4.77661E-06 | |
19336 | 53 | N/I | 70 | rs371851242 | 0.9903 | None | gnomAD-2.1.1 | 3.21E-05 | |
19336 | 53 | N/I | 70 | rs371851242 | 0.9903 | None | gnomAD-3.1.2 | 4.6E-05 | |
19336 | 53 | N/I | 70 | rs371851242 | 0.9903 | None | gnomAD-4.0.0 | 5.82666E-05 | |
19337 | 54 | D/E | 72 | None | 0.8730 | None | gnomAD-4.0.0 | 3.1844E-06 | |
19337 | 54 | D/N | 72 | rs1239348052 | 0.8730 | None | gnomAD-2.1.1 | 4.02E-06 | |
19337 | 54 | D/N | 72 | rs1239348052 | 0.8730 | None | gnomAD-4.0.0 | 1.59223E-06 | |
19339 | 56 | L/F | 77 | rs368025965 | 0.1355 | None | gnomAD-2.1.1 | 2.86E-05 | |
19339 | 56 | L/F | 77 | rs368025965 | 0.1355 | None | gnomAD-3.1.2 | 5.92E-05 | |
19339 | 56 | L/F | 77 | rs368025965 | 0.1355 | None | gnomAD-4.0.0 | 1.11578E-04 | |
19340 | 57 | L/H | 83 | rs777213118 | 0.5879 | None | gnomAD-2.1.1 | 7.14E-06 | |
19340 | 57 | L/H | 83 | rs777213118 | 0.5879 | None | gnomAD-3.1.2 | 6.58E-06 | |
19340 | 57 | L/H | 83 | rs777213118 | 0.5879 | None | gnomAD-4.0.0 | 1.11575E-05 | |
19341 | 58 | S/N | 88 | rs536645864 | 0.3646 | None | gnomAD-2.1.1 | 7.64E-05 | |
19341 | 58 | S/N | 88 | rs536645864 | 0.3646 | None | gnomAD-3.1.2 | 1.32E-05 | |
19341 | 58 | S/N | 88 | rs536645864 | 0.3646 | None | 1000 genomes | 1.99681E-04 | |
19341 | 58 | S/N | 88 | rs536645864 | 0.3646 | None | gnomAD-4.0.0 | 4.71078E-05 | |
19342 | 59 | R/I | 89 | None | 0.4124 | None | gnomAD-4.0.0 | 2.05311E-06 | |
19342 | 59 | R/K | 89 | None | 0.4124 | None | gnomAD-4.0.0 | 6.84371E-07 | |
19345 | 62 | T/A | 92 | rs567680958 | 0.2693 | None | gnomAD-2.1.1 | 3.62E-05 | |
19345 | 62 | T/A | 92 | rs567680958 | 0.2693 | None | gnomAD-3.1.2 | 6.57E-06 | |
19345 | 62 | T/A | 92 | rs567680958 | 0.2693 | None | 1000 genomes | 1.99681E-04 | |
19345 | 62 | T/A | 92 | rs567680958 | 0.2693 | None | gnomAD-4.0.0 | 1.17765E-05 | |
19345 | 62 | T/I | 92 | rs551040385 | 0.2693 | None | gnomAD-2.1.1 | 4.02E-06 | |
19345 | 62 | T/I | 92 | rs551040385 | 0.2693 | None | gnomAD-3.1.2 | 6.58E-06 | |
19345 | 62 | T/I | 92 | rs551040385 | 0.2693 | None | 1000 genomes | 1.99681E-04 | |
19345 | 62 | T/I | 92 | rs551040385 | 0.2693 | None | gnomAD-4.0.0 | 6.57212E-06 | |
19345 | 62 | T/N | 92 | rs551040385 | 0.2693 | None | gnomAD-4.0.0 | 1.20033E-06 | |
19346 | 63 | V/A | 93 | rs754793079 | 0.1464 | None | gnomAD-2.1.1 | 4.02E-06 | |
19346 | 63 | V/A | 93 | rs754793079 | 0.1464 | None | gnomAD-4.0.0 | 2.12159E-05 | |
19346 | 63 | V/F | 93 | None | 0.1464 | None | gnomAD-4.0.0 | 3.60098E-06 | |
19346 | 63 | V/G | 93 | None | 0.1464 | None | gnomAD-4.0.0 | 6.84383E-07 | |
19348 | 65 | G/D | 96 | rs530742564 | 0.5738 | None | gnomAD-3.1.2 | 6.58E-06 | |
19348 | 65 | G/D | 96 | rs530742564 | 0.5738 | None | 1000 genomes | 1.99681E-04 | |
19348 | 65 | G/D | 96 | rs530742564 | 0.5738 | None | gnomAD-4.0.0 | 6.57376E-06 | |
19349 | 66 | L/F | 97 | None | 0.1640 | None | gnomAD-4.0.0 | 1.20033E-06 | |
19351 | 68 | E/D | 99 | None | 0.5711 | None | gnomAD-4.0.0 | 3.18562E-06 | |
19352 | 69 | G/D | 100 | rs995136716 | 0.3778 | None | gnomAD-4.0.0 | 6.8451E-07 | |
19353 | 70 | D/N | 102 | None | 0.3156 | None | gnomAD-4.0.0 | 1.20032E-06 | |
19354 | 71 | T/N | 103 | None | 0.1823 | None | gnomAD-4.0.0 | 1.20033E-06 | |
19355 | 72 | Y/C | 104 | rs766593902 | 0.1519 | None | gnomAD-2.1.1 | 1.61E-05 | |
19355 | 72 | Y/C | 104 | rs766593902 | 0.1519 | None | gnomAD-3.1.2 | 6.57E-06 | |
19355 | 72 | Y/C | 104 | rs766593902 | 0.1519 | None | gnomAD-4.0.0 | 9.92088E-06 | |
19355 | 72 | Y/F | 104 | None | 0.1519 | None | gnomAD-4.0.0 | 6.84634E-07 | |
19356 | 73 | E/D | 105 | None | 0.1825 | None | gnomAD-4.0.0 | 8.40229E-06 | |
19357 | 74 | Y/C | 106 | rs373907843 | 0.1186 | None | gnomAD-2.1.1 | 1.62E-05 | |
19357 | 74 | Y/C | 106 | rs373907843 | 0.1186 | None | gnomAD-3.1.2 | 3.29E-05 | |
19357 | 74 | Y/C | 106 | rs373907843 | 0.1186 | None | gnomAD-4.0.0 | 8.98118E-06 | |
19358 | 75 | R/C | 107 | rs371973579 | 0.1776 | None | gnomAD-2.1.1 | 1.14861E-04 | |
19358 | 75 | R/C | 107 | rs371973579 | 0.1776 | None | gnomAD-3.1.2 | 1.90737E-04 | |
19358 | 75 | R/C | 107 | rs371973579 | 0.1776 | None | 1000 genomes | 5.99042E-04 | |
19358 | 75 | R/C | 107 | rs371973579 | 0.1776 | None | gnomAD-4.0.0 | 4.71491E-05 | |
19358 | 75 | R/H | 107 | rs1023184567 | 0.1776 | None | gnomAD-2.1.1 | 1.21E-05 | |
19358 | 75 | R/H | 107 | rs1023184567 | 0.1776 | None | gnomAD-3.1.2 | 4.6E-05 | |
19358 | 75 | R/H | 107 | rs1023184567 | 0.1776 | None | gnomAD-4.0.0 | 2.54385E-05 | |
19360 | 77 | S/N | 109 | rs761996172 | 0.0977 | None | gnomAD-2.1.1 | 8.13E-06 | |
19360 | 77 | S/N | 109 | rs761996172 | 0.0977 | None | gnomAD-4.0.0 | 3.20004E-06 | |
19361 | 78 | A/T | 110 | None | 0.0790 | None | gnomAD-4.0.0 | 1.20032E-06 | |
19362 | 79 | V/F | 111 | rs878854321 | 0.1316 | None | gnomAD-2.1.1 | 4.08E-06 | |
19362 | 79 | V/F | 111 | rs878854321 | 0.1316 | None | gnomAD-4.0.0 | 6.86932E-07 | |
19362 | 79 | V/I | 111 | None | 0.1316 | None | gnomAD-4.0.0 | 1.37386E-06 | |
19363 | 80 | N/S | 112 | rs777181856 | 0.0844 | None | gnomAD-2.1.1 | 8.19E-06 | |
19363 | 80 | N/S | 112 | rs777181856 | 0.0844 | None | gnomAD-3.1.2 | 6.57E-06 | |
19363 | 80 | N/S | 112 | rs777181856 | 0.0844 | None | gnomAD-4.0.0 | 7.46796E-06 | |
19364 | 81 | I/M | 113 | rs182489815 | 0.6333 | None | gnomAD-2.1.1 | 4.09E-06 | |
19364 | 81 | I/M | 113 | rs182489815 | 0.6333 | None | gnomAD-3.1.2 | 1.31E-05 | |
19364 | 81 | I/M | 113 | rs182489815 | 0.6333 | None | 1000 genomes | 1.99681E-04 | |
19364 | 81 | I/M | 113 | rs182489815 | 0.6333 | None | gnomAD-4.0.0 | 1.31392E-05 | |
19364 | 81 | I/N | 113 | rs1239668517 | 0.6333 | None | gnomAD-2.1.1 | 4.09E-06 | |
19364 | 81 | I/N | 113 | rs1239668517 | 0.6333 | None | gnomAD-3.1.2 | 6.57E-06 | |
19364 | 81 | I/N | 113 | rs1239668517 | 0.6333 | None | gnomAD-4.0.0 | 4.35677E-06 | |
19364 | 81 | I/V | 113 | rs1472130936 | 0.6333 | None | gnomAD-2.1.1 | 4.09E-06 | |
19364 | 81 | I/V | 113 | rs1472130936 | 0.6333 | None | gnomAD-4.0.0 | 3.21792E-06 | |
19368 | 85 | G/D | 118 | rs772445847 | 0.1756 | None | gnomAD-4.0.0 | 1.61572E-06 | |
19369 | 86 | K/E | 119 | rs759447234 | 0.8280 | None | gnomAD-3.1.2 | 6.57E-06 | |
19369 | 86 | K/E | 119 | rs759447234 | 0.8280 | None | gnomAD-4.0.0 | 1.43457E-05 | |
19370 | 87 | P/A | 120 | None | 0.3276 | None | gnomAD-4.0.0 | 1.37864E-06 | |
19370 | 87 | P/T | 120 | rs890232785 | 0.3276 | None | gnomAD-4.0.0 | 6.8932E-07 | |
19373 | 90 | C/F | 123 | None | 0.3043 | None | gnomAD-4.0.0 | 2.07463E-06 | |
19373 | 90 | C/R | 123 | None | 0.3043 | None | gnomAD-4.0.0 | 1.62759E-06 | |
19374 | 91 | T/A | 124 | None | 0.1658 | None | gnomAD-4.0.0 | 1.63015E-06 | |
19374 | 91 | T/S | 124 | rs794729463 | 0.1658 | None | gnomAD-2.1.1 | 6.37E-05 | |
19374 | 91 | T/S | 124 | rs794729463 | 0.1658 | None | gnomAD-3.1.2 | 1.97E-05 | |
19374 | 91 | T/S | 124 | rs794729463 | 0.1658 | None | gnomAD-4.0.0 | 6.53395E-06 | |
19375 | 92 | K/R | 125 | rs374594411 | 0.9214 | None | gnomAD-2.1.1 | 2.61E-05 | |
19375 | 92 | K/R | 125 | rs374594411 | 0.9214 | None | gnomAD-3.1.2 | 3.95E-05 | |
19375 | 92 | K/R | 125 | rs374594411 | 0.9214 | None | gnomAD-4.0.0 | 1.75368E-05 | |
19376 | 93 | P/S | 126 | None | 0.4293 | None | gnomAD-4.0.0 | 3.46185E-06 | |
19376 | 93 | P/T | 126 | rs1226665355 | 0.4293 | None | gnomAD-2.1.1 | 4.23E-06 | |
19378 | 95 | T/I | 129 | rs371456511 | 0.3160 | None | gnomAD-2.1.1 | 8.56E-06 | |
19378 | 95 | T/I | 129 | rs371456511 | 0.3160 | None | gnomAD-4.0.0 | 6.56955E-06 | |
19379 | 96 | C/F | 130 | None | 0.0808 | None | gnomAD-4.0.0 | 6.94046E-07 | |
19380 | 97 | K/T | 131 | rs1245279855 | 0.5968 | None | gnomAD-2.1.1 | 4.3E-06 | |
19380 | 97 | K/T | 131 | rs1245279855 | 0.5968 | None | gnomAD-4.0.0 | 1.64569E-06 | |
19381 | 98 | D/E | 132 | None | 0.6923 | None | gnomAD-4.0.0 | 1.20035E-06 | |
19381 | 98 | D/N | 132 | rs1325584288 | 0.6923 | None | gnomAD-2.1.1 | 4.3E-06 | |
19381 | 98 | D/N | 132 | rs1325584288 | 0.6923 | None | gnomAD-4.0.0 | 1.64633E-06 |